The Diagnostic Value of Sonographic Findings in Axillary Lymphadenopathy

Elif Colak; Gultekin Ozan Kucuk; Kadir Yildirim; Onur Ozturk

doi:doi:10.11648/j.jfmhc.20150102.11

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The Diagnostic Value of Sonographic Findings in Axillary Lymphadenopathy

Elif Colak, Gultekin Ozan Kucuk, Kadir Yildirim, Onur Ozturk

Published in Journal of Family Medicine and Health Care (Volume 1, Issue 2)

Received: 31 July 2015 Accepted: 6 August 2015 Published: 11 August 2015

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Abstract

Background: Axillary lymphadenopathy (LAP) is one of the most common pathologies encountered in daily practice. The aim of this study is to evaluate the demographic, ultrasonographic, and biopsy findings of patients who underwent an excisional biopsy to distinguish between benign and malignant LAP of the axillary region. Methods: Patients who underwent an excisional biopsy between January 2008 and June 2013 in Samsun Education and Research Hospital were evaluated retrospectively. The exclusion criterion was patients who were diagnosed with breast cancer before admission. According to their pathology results, 23 patients were classified as Group 1 (n=4) and Group 2 (n=19) based on the presence of malignant and benign lymph node involvement, respectively. The demographic data (age and gender) and ultrasonographic findings (shape, diameter, and number of lymph nodes) of the two groups were then compared. Results: Seventeen (73.91%) of the patients were female, and 6 (26.09%) were male. According to the pathology results, a malignant lymphoma was diagnosed in four patients in Group 1. Granulomatous lymphadenitis (n=6) and reactive lymphadenitis (n=13) were diagnosed in Group 2. There was no statistical difference between the groups in terms of age (55 vs 47 years). There was a statistically significant between-group difference in gender, with a male gender predominance in the malignant lymphoma group (p=0.04). In Group 1, all the patients (100%) had multiple enlarged lymph nodes, whereas only 11 (57.8%) of the patients in Group 2 had multiple enlarged lymph nodes. There was no significant difference between the groups in the numbers of lymph nodes (p=0.15). There was statistically significant difference between groups in terms of lymph node diameter (45 vs 26 mm) (p=0.02). Conclusion: Ultrasonography (US) is a valuable tool in the diagnosis of patients with axillary LAP. Our findings suggest that a histopathological examination is warranted in male patients with an axillary LAP larger than 2 cm determined by US

Published in	Journal of Family Medicine and Health Care (Volume 1, Issue 2)
DOI	10.11648/j.jfmhc.20150102.11
Page(s)	21-23
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2015. Published by Science Publishing Group

Keywords

Axilla, Lymphadenopathy, Ultrasonography, Pathology, Lymphoma

References

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[2]	Singh S, Mishra AK, Tewari S, Kumar S (2013) Bilateral axillary masses mimicking as accessory breast with multiple fibroadenoma and bilateral gigantomastia in HIV-positive patient. BMJ Case Rep 2013.
[3]	De Andrade JM, Marana HR, Sarmento Filho JM, Murta EF, Velludo MA, et al. (1996) Differential diagnosis of axillary masses. Tumori 82: 596-599.
[4]	Verbanck J, Vandewiele I, De Winter H, Tytgat J, Van Aelst F, et al. (1997) Value of axillary ultrasonography and sonographically guided puncture of axillary nodes: a prospective study in 144 consecutive patients. J Clin Ultrasound 25: 53-56.
[5]	Feu J, Tresserra F, Fabregas R, Navarro B, Grases PJ, et al. (1997) Metastatic breast carcinoma in axillary lymph nodes: in vitro US detection. Radiology 205: 831-835.
[6]	Rubaltelli L, Proto E, Salmaso R, Bortoletto P, Candiani F, et al. (1990) Sonography of abnormal lymph nodes in vitro: correlation of sonographic and histologic findings. AJR Am J Roentgenol 155: 1241-1244.
[7]	Hrazdira I, Krupova M, Kyselova H (2005) [Possibilities of ultrasonographic differentiation of neck and axillary lymphadenopathy]. Vnitr Lek 51: 1371-1374.
[8]	Fanny ML, Beyam N, Gody JC, Zandanga G, Yango F, et al. (2012) Fine-needle aspiration for diagnosis of tuberculous lymphadenitis in children in Bangui, Central African Republic. BMC Pediatr 12: 191.
[9]	Marti JL, Ayo D, Levine P, Hernandez O, Rescigno J, et al. (2012) Nonimage-guided fine needle aspiration biopsy of palpable axillary lymph nodes in breast cancer patients. Breast J 18: 3-7.
[10]	Hirachand S, Lakhey M, Akhter J, Thapa B (2009) Evaluation of fine needle aspiration cytology of lymph nodes in Kathmandu Medical College, Teaching hospital. Kathmandu Univ Med J (KUMJ) 7: 139-142.
[11]	Lee Y, Terry R, Lukes RJ (1980) Lymph node biopsy for diagnosis: a statistical study. J Surg Oncol 14: 53-60.
[12]	Bazemore AW, Smucker DR (2002) Lymphadenopathy and malignancy. Am Fam Physician 66: 2103-2110.
[13]	Castillo JJ, Winer ES, Olszewski AJ (2013) Population-based prognostic factors for survival in patients with Burkitt lymphoma: an analysis from the Surveillance, Epidemiology, and End Results database. Cancer 119: 3672-3679.
[14]	Wan WL, Tian L, Wang J, Zhang W, Jing HM, et al. (2013) [Clinical characteristics and prognostic factors of 62 cases with Hodgkin lymphoma]. Zhonghua Xue Ye Xue Za Zhi 34: 618-621.
[15]	Vassilakopoulos TP, Pangalis GA (2000) Application of a prediction rule to select which patients presenting with lymphadenopathy should undergo a lymph node biopsy. Medicine (Baltimore) 79: 338-347.
[16]	Slap GB, Brooks JS, Schwartz JS (1984) When to perform biopsies of enlarged peripheral lymph nodes in young patients. JAMA 252: 1321-1326.

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APA Style

Elif Colak, Gultekin Ozan Kucuk, Kadir Yildirim, Onur Ozturk. (2015). The Diagnostic Value of Sonographic Findings in Axillary Lymphadenopathy. Journal of Family Medicine and Health Care, 1(2), 21-23. https://doi.org/10.11648/j.jfmhc.20150102.11

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ACS Style

Elif Colak; Gultekin Ozan Kucuk; Kadir Yildirim; Onur Ozturk. The Diagnostic Value of Sonographic Findings in Axillary Lymphadenopathy. J. Fam. Med. Health Care 2015, 1(2), 21-23. doi: 10.11648/j.jfmhc.20150102.11

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AMA Style

Elif Colak, Gultekin Ozan Kucuk, Kadir Yildirim, Onur Ozturk. The Diagnostic Value of Sonographic Findings in Axillary Lymphadenopathy. J Fam Med Health Care. 2015;1(2):21-23. doi: 10.11648/j.jfmhc.20150102.11

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@article{10.11648/j.jfmhc.20150102.11,
  author = {Elif Colak and Gultekin Ozan Kucuk and Kadir Yildirim and Onur Ozturk},
  title = {The Diagnostic Value of Sonographic Findings in Axillary Lymphadenopathy},
  journal = {Journal of Family Medicine and Health Care},
  volume = {1},
  number = {2},
  pages = {21-23},
  doi = {10.11648/j.jfmhc.20150102.11},
  url = {https://doi.org/10.11648/j.jfmhc.20150102.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.jfmhc.20150102.11},
  abstract = {Background: Axillary lymphadenopathy (LAP) is one of the most common pathologies encountered in daily practice. The aim of this study is to evaluate the demographic, ultrasonographic, and biopsy findings of patients who underwent an excisional biopsy to distinguish between benign and malignant LAP of the axillary region. Methods: Patients who underwent an excisional biopsy between January 2008 and June 2013 in Samsun Education and Research Hospital were evaluated retrospectively. The exclusion criterion was patients who were diagnosed with breast cancer before admission. According to their pathology results, 23 patients were classified as Group 1 (n=4) and Group 2 (n=19) based on the presence of malignant and benign lymph node involvement, respectively. The demographic data (age and gender) and ultrasonographic findings (shape, diameter, and number of lymph nodes) of the two groups were then compared. Results: Seventeen (73.91%) of the patients were female, and 6 (26.09%) were male. According to the pathology results, a malignant lymphoma was diagnosed in four patients in Group 1. Granulomatous lymphadenitis (n=6) and reactive lymphadenitis (n=13) were diagnosed in Group 2. There was no statistical difference between the groups in terms of age (55 vs 47 years). There was a statistically significant between-group difference in gender, with a male gender predominance in the malignant lymphoma group (p=0.04). In Group 1, all the patients (100%) had multiple enlarged lymph nodes, whereas only 11 (57.8%) of the patients in Group 2 had multiple enlarged lymph nodes. There was no significant difference between the groups in the numbers of lymph nodes (p=0.15). There was statistically significant difference between groups in terms of lymph node diameter (45 vs 26 mm) (p=0.02). Conclusion: Ultrasonography (US) is a valuable tool in the diagnosis of patients with axillary LAP. Our findings suggest that a histopathological examination is warranted in male patients with an axillary LAP larger than 2 cm determined by US},
 year = {2015}
}

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TY  - JOUR
T1  - The Diagnostic Value of Sonographic Findings in Axillary Lymphadenopathy
AU  - Elif Colak
AU  - Gultekin Ozan Kucuk
AU  - Kadir Yildirim
AU  - Onur Ozturk
Y1  - 2015/08/11
PY  - 2015
N1  - https://doi.org/10.11648/j.jfmhc.20150102.11
DO  - 10.11648/j.jfmhc.20150102.11
T2  - Journal of Family Medicine and Health Care
JF  - Journal of Family Medicine and Health Care
JO  - Journal of Family Medicine and Health Care
SP  - 21
EP  - 23
PB  - Science Publishing Group
SN  - 2469-8342
UR  - https://doi.org/10.11648/j.jfmhc.20150102.11
AB  - Background: Axillary lymphadenopathy (LAP) is one of the most common pathologies encountered in daily practice. The aim of this study is to evaluate the demographic, ultrasonographic, and biopsy findings of patients who underwent an excisional biopsy to distinguish between benign and malignant LAP of the axillary region. Methods: Patients who underwent an excisional biopsy between January 2008 and June 2013 in Samsun Education and Research Hospital were evaluated retrospectively. The exclusion criterion was patients who were diagnosed with breast cancer before admission. According to their pathology results, 23 patients were classified as Group 1 (n=4) and Group 2 (n=19) based on the presence of malignant and benign lymph node involvement, respectively. The demographic data (age and gender) and ultrasonographic findings (shape, diameter, and number of lymph nodes) of the two groups were then compared. Results: Seventeen (73.91%) of the patients were female, and 6 (26.09%) were male. According to the pathology results, a malignant lymphoma was diagnosed in four patients in Group 1. Granulomatous lymphadenitis (n=6) and reactive lymphadenitis (n=13) were diagnosed in Group 2. There was no statistical difference between the groups in terms of age (55 vs 47 years). There was a statistically significant between-group difference in gender, with a male gender predominance in the malignant lymphoma group (p=0.04). In Group 1, all the patients (100%) had multiple enlarged lymph nodes, whereas only 11 (57.8%) of the patients in Group 2 had multiple enlarged lymph nodes. There was no significant difference between the groups in the numbers of lymph nodes (p=0.15). There was statistically significant difference between groups in terms of lymph node diameter (45 vs 26 mm) (p=0.02). Conclusion: Ultrasonography (US) is a valuable tool in the diagnosis of patients with axillary LAP. Our findings suggest that a histopathological examination is warranted in male patients with an axillary LAP larger than 2 cm determined by US
VL  - 1
IS  - 2
ER  -

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Author Information

Elif Colak

Department of General Surgery, Samsun Education and Research Hospital, Samsun, Turkey
Gultekin Ozan Kucuk

Department of General Surgery, Samsun Education and Research Hospital, Samsun, Turkey
Kadir Yildirim

Department of General Surgery, Samsun Education and Research Hospital, Samsun, Turkey
Onur Ozturk

Asarcik Community Health Center, Samsun, Turkey

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APA Style

Elif Colak, Gultekin Ozan Kucuk, Kadir Yildirim, Onur Ozturk. (2015). The Diagnostic Value of Sonographic Findings in Axillary Lymphadenopathy. Journal of Family Medicine and Health Care, 1(2), 21-23. https://doi.org/10.11648/j.jfmhc.20150102.11

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ACS Style

Elif Colak; Gultekin Ozan Kucuk; Kadir Yildirim; Onur Ozturk. The Diagnostic Value of Sonographic Findings in Axillary Lymphadenopathy. J. Fam. Med. Health Care 2015, 1(2), 21-23. doi: 10.11648/j.jfmhc.20150102.11

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AMA Style

Elif Colak, Gultekin Ozan Kucuk, Kadir Yildirim, Onur Ozturk. The Diagnostic Value of Sonographic Findings in Axillary Lymphadenopathy. J Fam Med Health Care. 2015;1(2):21-23. doi: 10.11648/j.jfmhc.20150102.11

Copy | Download

@article{10.11648/j.jfmhc.20150102.11,
  author = {Elif Colak and Gultekin Ozan Kucuk and Kadir Yildirim and Onur Ozturk},
  title = {The Diagnostic Value of Sonographic Findings in Axillary Lymphadenopathy},
  journal = {Journal of Family Medicine and Health Care},
  volume = {1},
  number = {2},
  pages = {21-23},
  doi = {10.11648/j.jfmhc.20150102.11},
  url = {https://doi.org/10.11648/j.jfmhc.20150102.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.jfmhc.20150102.11},
  abstract = {Background: Axillary lymphadenopathy (LAP) is one of the most common pathologies encountered in daily practice. The aim of this study is to evaluate the demographic, ultrasonographic, and biopsy findings of patients who underwent an excisional biopsy to distinguish between benign and malignant LAP of the axillary region. Methods: Patients who underwent an excisional biopsy between January 2008 and June 2013 in Samsun Education and Research Hospital were evaluated retrospectively. The exclusion criterion was patients who were diagnosed with breast cancer before admission. According to their pathology results, 23 patients were classified as Group 1 (n=4) and Group 2 (n=19) based on the presence of malignant and benign lymph node involvement, respectively. The demographic data (age and gender) and ultrasonographic findings (shape, diameter, and number of lymph nodes) of the two groups were then compared. Results: Seventeen (73.91%) of the patients were female, and 6 (26.09%) were male. According to the pathology results, a malignant lymphoma was diagnosed in four patients in Group 1. Granulomatous lymphadenitis (n=6) and reactive lymphadenitis (n=13) were diagnosed in Group 2. There was no statistical difference between the groups in terms of age (55 vs 47 years). There was a statistically significant between-group difference in gender, with a male gender predominance in the malignant lymphoma group (p=0.04). In Group 1, all the patients (100%) had multiple enlarged lymph nodes, whereas only 11 (57.8%) of the patients in Group 2 had multiple enlarged lymph nodes. There was no significant difference between the groups in the numbers of lymph nodes (p=0.15). There was statistically significant difference between groups in terms of lymph node diameter (45 vs 26 mm) (p=0.02). Conclusion: Ultrasonography (US) is a valuable tool in the diagnosis of patients with axillary LAP. Our findings suggest that a histopathological examination is warranted in male patients with an axillary LAP larger than 2 cm determined by US},
 year = {2015}
}

Copy | Download

TY  - JOUR
T1  - The Diagnostic Value of Sonographic Findings in Axillary Lymphadenopathy
AU  - Elif Colak
AU  - Gultekin Ozan Kucuk
AU  - Kadir Yildirim
AU  - Onur Ozturk
Y1  - 2015/08/11
PY  - 2015
N1  - https://doi.org/10.11648/j.jfmhc.20150102.11
DO  - 10.11648/j.jfmhc.20150102.11
T2  - Journal of Family Medicine and Health Care
JF  - Journal of Family Medicine and Health Care
JO  - Journal of Family Medicine and Health Care
SP  - 21
EP  - 23
PB  - Science Publishing Group
SN  - 2469-8342
UR  - https://doi.org/10.11648/j.jfmhc.20150102.11
AB  - Background: Axillary lymphadenopathy (LAP) is one of the most common pathologies encountered in daily practice. The aim of this study is to evaluate the demographic, ultrasonographic, and biopsy findings of patients who underwent an excisional biopsy to distinguish between benign and malignant LAP of the axillary region. Methods: Patients who underwent an excisional biopsy between January 2008 and June 2013 in Samsun Education and Research Hospital were evaluated retrospectively. The exclusion criterion was patients who were diagnosed with breast cancer before admission. According to their pathology results, 23 patients were classified as Group 1 (n=4) and Group 2 (n=19) based on the presence of malignant and benign lymph node involvement, respectively. The demographic data (age and gender) and ultrasonographic findings (shape, diameter, and number of lymph nodes) of the two groups were then compared. Results: Seventeen (73.91%) of the patients were female, and 6 (26.09%) were male. According to the pathology results, a malignant lymphoma was diagnosed in four patients in Group 1. Granulomatous lymphadenitis (n=6) and reactive lymphadenitis (n=13) were diagnosed in Group 2. There was no statistical difference between the groups in terms of age (55 vs 47 years). There was a statistically significant between-group difference in gender, with a male gender predominance in the malignant lymphoma group (p=0.04). In Group 1, all the patients (100%) had multiple enlarged lymph nodes, whereas only 11 (57.8%) of the patients in Group 2 had multiple enlarged lymph nodes. There was no significant difference between the groups in the numbers of lymph nodes (p=0.15). There was statistically significant difference between groups in terms of lymph node diameter (45 vs 26 mm) (p=0.02). Conclusion: Ultrasonography (US) is a valuable tool in the diagnosis of patients with axillary LAP. Our findings suggest that a histopathological examination is warranted in male patients with an axillary LAP larger than 2 cm determined by US
VL  - 1
IS  - 2
ER  -

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