Anti-streptolysin O (ASO) titer assists for the diagnosis of Group A, Group C and Group G streptococcal infections and their sequele. Reference value of Anti-streptolysin O titer is not available for Ethiopian populations. This study determined the upper limit of normal reference value in apparently healthy children. Participants with a history of streptococal disease were excluded. A total of 127 blood samples were collected from 127 participants with age range of 5-15 years. Serum was used to determine Anti-Streptolysin O-titers. The average ASO Upper limits of Normal (ULN) titer for the total participants was 360 IU/ml with a median 200 IU/ml. The ASO ULN for both male and female children was 320 IU/ml with a median of 200IU/ml. The highest ASO ULN was observed for the age group of 9-12 years (400 IU/ml with median of 200 IU/ml) followed by 360 IU/ml for the age group 5-8 years and age group 13-15 years with a median of 200 IU/ml. This finding shows that ASO ULN are similar to those reported in countries with different climates and populations. Package inserts interpreting ASO titer > 400 IU/ml as recent streptococcal infection is applicable for Ethiopian population.
| Published in | Journal of Family Medicine and Health Care (Volume 4, Issue 1) |
| DOI | 10.11648/j.jfmhc.20180401.11 |
| Page(s) | 1-4 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2018. Published by Science Publishing Group |
Children, Apparently Healthy, ASO Titers, Ethiopia
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APA Style
Tsegahun Asfaw, Demissew Shenkute, Mihret Tilahun, Nigus Zegeye. (2018). Antistreptolysin O Titers: Normal Values for Children Ages 5 to 15 at Debre Berhan Referral Hospital, Ethiopia. Journal of Family Medicine and Health Care, 4(1), 1-4. https://doi.org/10.11648/j.jfmhc.20180401.11
ACS Style
Tsegahun Asfaw; Demissew Shenkute; Mihret Tilahun; Nigus Zegeye. Antistreptolysin O Titers: Normal Values for Children Ages 5 to 15 at Debre Berhan Referral Hospital, Ethiopia. J. Fam. Med. Health Care 2018, 4(1), 1-4. doi: 10.11648/j.jfmhc.20180401.11
AMA Style
Tsegahun Asfaw, Demissew Shenkute, Mihret Tilahun, Nigus Zegeye. Antistreptolysin O Titers: Normal Values for Children Ages 5 to 15 at Debre Berhan Referral Hospital, Ethiopia. J Fam Med Health Care. 2018;4(1):1-4. doi: 10.11648/j.jfmhc.20180401.11
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Download@article{10.11648/j.jfmhc.20180401.11,
author = {Tsegahun Asfaw and Demissew Shenkute and Mihret Tilahun and Nigus Zegeye},
title = {Antistreptolysin O Titers: Normal Values for Children Ages 5 to 15 at Debre Berhan Referral Hospital, Ethiopia},
journal = {Journal of Family Medicine and Health Care},
volume = {4},
number = {1},
pages = {1-4},
doi = {10.11648/j.jfmhc.20180401.11},
url = {https://doi.org/10.11648/j.jfmhc.20180401.11},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.jfmhc.20180401.11},
abstract = {Anti-streptolysin O (ASO) titer assists for the diagnosis of Group A, Group C and Group G streptococcal infections and their sequele. Reference value of Anti-streptolysin O titer is not available for Ethiopian populations. This study determined the upper limit of normal reference value in apparently healthy children. Participants with a history of streptococal disease were excluded. A total of 127 blood samples were collected from 127 participants with age range of 5-15 years. Serum was used to determine Anti-Streptolysin O-titers. The average ASO Upper limits of Normal (ULN) titer for the total participants was 360 IU/ml with a median 200 IU/ml. The ASO ULN for both male and female children was 320 IU/ml with a median of 200IU/ml. The highest ASO ULN was observed for the age group of 9-12 years (400 IU/ml with median of 200 IU/ml) followed by 360 IU/ml for the age group 5-8 years and age group 13-15 years with a median of 200 IU/ml. This finding shows that ASO ULN are similar to those reported in countries with different climates and populations. Package inserts interpreting ASO titer > 400 IU/ml as recent streptococcal infection is applicable for Ethiopian population.},
year = {2018}
}
TY - JOUR T1 - Antistreptolysin O Titers: Normal Values for Children Ages 5 to 15 at Debre Berhan Referral Hospital, Ethiopia AU - Tsegahun Asfaw AU - Demissew Shenkute AU - Mihret Tilahun AU - Nigus Zegeye Y1 - 2018/04/20 PY - 2018 N1 - https://doi.org/10.11648/j.jfmhc.20180401.11 DO - 10.11648/j.jfmhc.20180401.11 T2 - Journal of Family Medicine and Health Care JF - Journal of Family Medicine and Health Care JO - Journal of Family Medicine and Health Care SP - 1 EP - 4 PB - Science Publishing Group SN - 2469-8342 UR - https://doi.org/10.11648/j.jfmhc.20180401.11 AB - Anti-streptolysin O (ASO) titer assists for the diagnosis of Group A, Group C and Group G streptococcal infections and their sequele. Reference value of Anti-streptolysin O titer is not available for Ethiopian populations. This study determined the upper limit of normal reference value in apparently healthy children. Participants with a history of streptococal disease were excluded. A total of 127 blood samples were collected from 127 participants with age range of 5-15 years. Serum was used to determine Anti-Streptolysin O-titers. The average ASO Upper limits of Normal (ULN) titer for the total participants was 360 IU/ml with a median 200 IU/ml. The ASO ULN for both male and female children was 320 IU/ml with a median of 200IU/ml. The highest ASO ULN was observed for the age group of 9-12 years (400 IU/ml with median of 200 IU/ml) followed by 360 IU/ml for the age group 5-8 years and age group 13-15 years with a median of 200 IU/ml. This finding shows that ASO ULN are similar to those reported in countries with different climates and populations. Package inserts interpreting ASO titer > 400 IU/ml as recent streptococcal infection is applicable for Ethiopian population. VL - 4 IS - 1 ER -
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